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ACTIV.A.C.™ Negative Pressure Wound Therapy System

The information on this page is intended for healthcare professionals. Patient-specific information is available in the “Patients” section of this site. Patients should consult a healthcare professional regarding specific medical conditions and treatments.

ACTIV.A.C.™ Therapy Unit
ACTIV.A.C.™ Therapy Unit
ACTIV.A.C.™ Therapy System
ACTIV.A.C.™ Therapy System

The ACTIV.A.C.™ Therapy System Is a Portable Negative Pressure Wound Therapy System Designed for Ambulatory Patients 

Designed to help patients resume their activities of daily living while still receiving the proven wound healing benefits of V.A.C.® Therapy. 
  • Creates an environment that promotes wound healing by facilitating granulation tissue formation
  • Ergonomic design is lightweight, small, and easy to use



Only V.A.C.® Therapy provides patented SENSAT.R.A.C.™ Technology, a real-time pressure feedback system that adjusts pump output, compensating for wound distance, wound position, exudates characteristics, and patient movement.


Designed to help clinicians and patients identify and troubleshoot dressing leaks
  • Instant feedback: Audio and visual cues are delivered in real-time, allowing easy location of dressing leaks
  • Therapy confidence: A proper seal helps ensure prescribed negative pressure for optimal wound healing
  • Possible reduction of unscheduled visits: Easier for clinicians to help troubleshoot problems over the phone

Therapy History Reporting

Documents patient compliance with V.A.C.® Therapy
  • Monitors therapy usage, settings, durations and dressing and canister changes to help ensure patients are receiving the prescribed course of therapy
  • USB port for convenient data downloads

How it Works

  • About
  • Specifications
  • Materials For Download


V.A.C.® Therapy provides an environment that promotes wound healing

The mechanisms of action for V.A.C.® Therapy include drawing wound edges together, removing infectious materials and wound fluids, promoting perfusion, maintaining a closed, moist wound healing environment and promoting granulation tissue formation.
The integrated V.A.C.® Therapy System has a unique mechanism of action whereby the delivery of negative pressure through the V.A.C.® Therapy Units using proprietary V.A.C.® GRANUFOAM™ Dressings maintains a wound environment that promotes wound healing.

How V.A.C.® Therapy creates an environment that promotes wound healing

Under negative pressure, V.A.C.® Therapy with proprietary V.A.C.® GRANUFOAM™ Dressings applies mechanical forces to the wound to create an environment that promotes wound healing. These forces are known as macrostrain and microstrain.1
Macrostrain is the visible stretch that occurs when negative pressure contracts the foam.
  • Draws wound edges together
  • Provides direct and complete wound bed contact
  • Evenly distributes negative pressure
  • Removes exudate and infectious materials
Microstrain is the microdeformation at the cellular level, which leads to cell stretch.
  • Reduces edema
  • Promotes perfusion
  • Promotes granulation tissue formation by facilitating cell migration and proliferation


ACTIV.A.C. Therapy Unit
Weight:                                 2.4lbs (1.08kg) with an empty canister
Dimensions:                          7.6”W x 6”H x 2.5”D ....(19.3 x 15.2 x 6.4cm)
Battery Type:                        Lithium ion rechargeable battery
Battery Life:                          14 hours average, depending on settings
Recharging Time:                 6 hours max
Canister Size:                        300ml
Therapy Delivery Modes:     Continuous or Intermittent
Intensity Settings:                Low, Medium, High
Therapy Pressure Options:  -25mmHg to -200mmHg (-3.3kPa to -26.6kPa)
Electrical Data
External Power Supply Input:                100-240V AC .72A @ 115V AC 47-63Hz
External Power Supply Output:             12V, 3.3A
Patient & Enclosure Leakage Current:  <100Microamps
IEC Classification
Type B, Applied Part Class II IPX0
Equipment not suitable for use in presence of flammable anesthetic mixture with air, oxygen or nitrous oxide.
Storage Conditions
Temperature Range:          -4°F (-20°C) to 140°F (60°C)
Relative Humidity Range:  0-95% non-condensing
Operating Conditions
Temperature Range:          41°F (5°C) to 104°F (40°C)
Relative Humidity Range:  0-95% non-condensing
Altitude Range:                   0 to 14,000 feet (0 to 4,267m)
Optimum Performance:     0 to 8,000 feet (0 to 2,438m)

Indications & Applications

Indications & Applications

  • Indications
  • Applications

Indications for Use

Before use, physicians should review complete risk information and essential prescribing information which can be found in the Instructions for Use
The V.A.C.® Therapy System is an integrated wound management system for use in acute, extended and home care settings. It is intended to create an environment that promotes wound healing by secondary or tertiary (delayed primary) intention by preparing the wound bed for closure, reducing edema, promoting granulation tissue formation and perfusion, and by removing exudate and infectious material. It is indicated for patients with chronic, acute, traumatic, subacute and dehisced wounds, partial-thickness burns, ulcers (such as diabetic, venous insufficiency or pressure), flaps and grafts.
When used on closed surgical incisions, it is intended to manage the environment of surgical incisions that continue to drain following sutured or staple closure by maintaining a closed environment and removing exudates via the application of negative pressure wound therapy.


Applying the V.A.C.® Therapy System to a Small Wound
Applying the V.A.C.® Therapy System to a Small Wound

Evidence & Outcomes

V.A.C.® Therapy has the largest body of evidence to date including over 1,000 peer reviewed articles, 45 of which are randomized controlled trials (RCTs). These studies have demonstrated the positive clinical outcomes of Negative Pressure Wound Therapy, as well as the effectiveness of V.A.C.® Therapy in managing diabetic foot wounds, chronic wounds (eg, pressure ulcers and lower extremity ulcers), and a variety of acute wounds. Some of these studies are listed below.

Clinical Evidence

Additional summary of evidence and outcomes.

Evidence & Outcomes

Evidence & Outcomes

Title Study Type Date Authors